Hydroxyethyl Starch or Saline for Fluid Resuscitation in Intensive Care

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منابع مشابه

Hydroxyethyl starch or saline for fluid resuscitation in intensive care.

BACKGROUND The safety and efficacy of hydroxyethyl starch (HES) for fluid resuscitation have not been fully evaluated, and adverse effects of HES on survival and renal function have been reported. METHODS We randomly assigned 7000 patients who had been admitted to an intensive care unit (ICU) in a 1:1 ratio to receive either 6% HES with a molecular weight of 130 kD and a molar substitution ra...

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Hydroxyethyl starch for fluid resuscitation in critically ill patients.

BACKGROUND Intravenous fluid therapy is one of the most frequent interventions provided to patients in the intensive care unit; however, the type of fluid (i.e., crystalloid or colloid) used for resuscitation remains controversial. The most common type of colloid administered to resuscitate critically ill patients is hydroxyethyl starch (HES); however, its safety and efficacy have not been rigo...

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Comparison of Albumin and Saline for Fluid Resuscitation in the Intensive Care Unit

Intervention: Patients were randomly assigned to receive either 4% albumin or normal saline, with randomization stratified according to institution and whether there was a diagnosis of trauma on admission to the ICU. Study fluids were supplied in identical 500-ml bottles, and blinding was ensured through the use of specially designed masking cartons and specially designed and manufactured admin...

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A Comparison of Albumin and Saline for Fluid Resuscitation in the Intensive Care Unit

The Saline versus Albumin Fluid Evaluation (SAFE) Study is a collaboration of the Australian and New Zealand Intensive Care Society Clinical Trials Group, the Australian Red Cross Blood Service, and the George Institute for International Health. The writing committee (Simon Finfer, M.B., B.S., Rinaldo Bellomo, M.B., B.S., M.D., Neil Boyce, M.B., B.S., Ph.D., Julie French, R.N., John Myburgh, M....

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A Comparison of Albumin and Saline for Fluid Resuscitation in the Intensive Care Unit

The Saline versus Albumin Fluid Evaluation (SAFE) Study is a collaboration of the Australian and New Zealand Intensive Care Society Clinical Trials Group, the Australian Red Cross Blood Service, and the George Institute for International Health. The writing committee (Simon Finfer, M.B., B.S., Rinaldo Bellomo, M.B., B.S., M.D., Neil Boyce, M.B., B.S., Ph.D., Julie French, R.N., John Myburgh, M....

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ژورنال

عنوان ژورنال: New England Journal of Medicine

سال: 2012

ISSN: 0028-4793,1533-4406

DOI: 10.1056/nejmoa1209759